王华峰，男，医学博士。现承担《遗传学》、《免疫学》等课程的教学。

一、主要研究方向：

主要研究方向是基础医学，涉及免疫炎症、肝损伤修复机制、肿瘤等方面。

二、主持或参加科研、教改项目

1.2018年山西省高等学校教学改革创新项目（山西省教育厅），J2018250，高中生物新课标中“表观遗传”模块的理解与传授，2018/05-2020/05，2万元（在研），主持

2.87978797威尼斯老品牌现代文理学院自然基金，2016KJYJ-6，某公司生产的蛋氨酸-胆碱缺乏饲料诱导的非酒精性脂肪性肝炎小鼠模型的构建与评价，2016/01- 2017 /12，1万元（结题），主持

3.国家自然科学基金委青年科学基金项目，31600730，C10orf90调节巨噬细胞极化和黑色素瘤免疫逃逸的作用机制研究，2017/01-2019/12，20万元（在研），参加

4.国家自然科学基金委面上项目，81272317、S100P调节胰腺癌免疫逃逸的作用机制研究、2013,01-2016,12、70万元（结题），参加科技部-国家重大科学研究计划（973重大）“肝癌治疗的新型纳米药物研究”项目子课题，2012CB932503、新型纳米药物调控肝癌免疫微环境的机制和药效学研究（已结题）、参加。

三、发表主要论文：

1.Wang Huafeng, Zhang Huan, Huang Biao, Miao Guolin, Yan Xiaoyan, Gao Gang, Luo Yongping, Chen Huize, Chen Wei, Yang Luhong. Mesenchymal stem cells reverse highfat dietinduced nonalcoholic fatty liver disease through suppression of CD4+ T lymphocytes in mice [J]. Molecular medicine reports, 2018, 17 (3): 3769-3774.

2.Cheng Xixi,Wang Huafeng, Yang Jinlai, Cheng Yingnan, Wang Dan, Yang Fengrui, Li Yan, Zhou Dongmei, Wang Yanxia, Xue Zhenyi, Zhang Lijuan, Zhang Qi, Yang Luhong, Zhang Rongxin, Da Yurong. Arctigenin protects against liver injury from acute hepatitis by suppressing immune cells in mice [J]. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 102: 464-471.（共一）

3.Huafeng Wang, Luhong Yang, Wang Dong, Zhang Qi, Lijuan Zhang. Pro-tumor activities of macrophages in the progression of melanoma [J].Human Vaccines & Immunotherapeutics, 2017, 13(7): 1556-1562.

4.Huafeng Wang, Lijuan Zhang, Luhong Yang, Chengfang Liu, Qi Zhang, Linjing Zhang. Targeting macrophage anti-tumor activity to suppress melanoma progression [J].Oncotarget, 2017, 8 (11): 18486-18496.

5.Wang Huafeng, Wang Dong, Yang Luhong, Wang Yanxia, Jia Junli, Na Dongchen, Chen Huize, Luo Yongping, Liu Chengfang. Compact bone-derived mesenchymal stem cells attenuate nonalcoholic steatohepatitis in a mouse model by modulation of CD4 cells differentiation [J].Int Immunopharmacol, 2017, 42: 67-73.

6.Wang Huafeng, Zhang Huan, Zhang Yuqing, Wang Dan, Cheng Xixi, Yang Fengrui, Zhang Qi, Xue Zhenyi, Li Yan, Zhang Lijuan, Yang Luhong, Miao Guolin, Li Daiqing, Guan Zhiyu, Da Yurong, Yao Zhi, Gao Fei, Qiao Liang, Kong Li, Zhang Rongxin. Plumbagin protects liver against fulminant hepatic failure and chronic liver fibrosis via inhibiting inflammation and collagen production [J]. Oncotarget,2016

7.Huafeng Wang, Huan Zhang, Zimu Zhang, Biao Huang, Xixi Cheng, Dan Wang, Zha la Gahu, Zhenyi Xue, Yurong Da, Daiqing Li, Zhi Yao, Fei Gao, Aimin Xu, and Rongxin Zhang, Adiponectin-derived active peptide ADP355 exerts anti-inflammatory and anti-fibrotic activities in thioacetamide-induced liver injury [J].Scientific reports, 2016, 6(19445)

8.Wang Dan,Wang Huafeng, Fu Shuyu, Cheng Xixi, Yang Fengrui, Zhang Qi, Li Yan, Xue Zhenyi, Zhang Lijuan, Hua.ng Wenjing, Yang Luhong, Na Dongchen, Da Yurong, Kong Ying, Zhang Rongxin. Parthenolide ameliorates Concanavalin A-induced acute hepatitis in mice and modulates the macrophages to an anti-inflammatory state [J].International Immunopharmacology, 2016, (38): 132-138.（共一）

9.Biao Huang, Xixi Cheng,Huafeng Wang, Wenjing Huang, Zha la Ga hu, Dan Wang, Kai Zhang, Huan Zhang, Zhenyi Xue, Yurong Da, Ning Zhang, Yongcheng Hu, Zhi Yao, Liang Qiao, Fei Gao, Rongxin Zhang, Mesenchymal stem cells and their secreted molecules predominantly ameliorate fulminant hepatic failure and chronic liver fibrosis in mice respectively [J].Journal of translational medicine, 2016, 14(1): 45（共一）

10.Zhenyi Xue, Wen Li,Huafeng Wang, Biao Huang, Zhenzhen Ge, Chao Gu, Ying Liu, Kai Zhang, Juhong Yang, Rong Han, Meiyu Peng, Yan Li, Da Zhang, Yurong Da, Zhi Yao, Rongxin Zhang, ZSTK474, a novel PI3K inhibitor, modulates human CD14+ monocyte-derived dendritic cell functions and suppresses experimental autoimmune encephalomyelitis [J].Journal of Molecular Medicine, 2014, 92(10): 1057-1068（共一）

11.Jia Long, Qing Xi,Huafeng Wang, Zimu Zhang, Hongkun Liu, Yingnan Cheng, Xiangdong Guo, Jieyou Zhang, Zhang Qi, Lijuan Zhang. miR-142-5p regulates tumor cell PD-L1 expression and enhances anti-tumor immunity [J].Biochemical & Biophysical Research Communications, 2017, 488(2): 425-431.

12.Kai Zhang, Zhenzhen Ge, Zhenyi Xue, Wenjing Huang, Mei Mei, Qi Zhang, Yan Li, Wen Li, Zhihui Zhang, Zimu Zhang, Lijuan Zhang,Huafeng Wang, Jinzhen Cai, Zhi Yao, Rongxin Zhang, Yurong Da, Chrysin suppresses human CD14+ monocyte-derived dendritic cells and ameliorates experimental autoimmune encephalomyelitis,Journal of Neuroimmunology, 2015 , 288:13-20

13.Kai Zhang, Zhenzhen Ge, Yurong Da, Dong Wang, Ying Liu, Zhenyi Xue, Yan Li, Wen Li, Lijuan Zhang,Huafeng Wang, Huan Zhanga, Meiyu Penga, b, c, d, Junwei Hao, Zhi Yao, Rongxin Zhang, Plumbagin suppresses dendritic cell functions and alleviates experimental autoimmune encephalomyelitis [J].Journal of Neuroimmunology, 2014, 273(1-2): 42-52

14.Xi Wu, Meiyu Peng, Bingqing Huang, Huan Zhang,Huafeng Wang, Biao Huang, Zhenyi Xue, Lijuan Zhang, Yurong Da, De Yang, Zhi Yao, Rongxin Zhang. Immune microenvironment profiles of tumor immune equilibrium and immune escape states of mouse sarcoma.Cancer Letters. 2013, 340:124–133

15.王华峰,任铎锋,刘玲.蜂王的分化发育与表观遗传[J].生物学通报,2018,53(11):6-8.

16.王华峰,刘玲,孙瑞娴,段江燕.切除了胸腺,还有体液免疫吗——从抗原出发[J].中学生物教学,2018(Z1):93-95.

17.王华峰,刘玲,孙瑞娴,芦荣胜.性格形成中的表观遗传机制[J].生物学教学, 2017(11).

18.王华峰,刘玲,卢荣胜.罗宾·霍利迪:表观遗传机制——DNA甲基化学说的提出者[J].中学生物教学,2017(10):45-46.

19.王华峰,孙瑞娴.表观遗传学的提出者——沃丁顿[J].中学生物教学,2017(06):50-51.

20.刘玲,孙瑞娴,徐应春,史江宁,王华峰.酵母细胞固定化实验的教学改进及建议[J].生物学通报,2016,51(12):42-43.（通讯作者），被人大书报资料中心复印报刊资料全文转载于2017年04期的《中学政治及其他学科的教与学》。